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Loss of grand histone H3 lysine 27 trimethylation domains mediated transcriptional activation in esophageal squamous cell carcinoma

Trimethylation of histone H3 lysine 27 trimethylation (H3K27me3) may be recruited by repressive Polycomb complexes to mediate gene silencing, which is critical for maintaining embryonic stem cell pluripotency and differentiation. However, the roles of aberrant H3K27me3 patterns in tumorigenesis are...

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Detalles Bibliográficos
Autores principales:	Yuan, Jian, Jiang, Qi, Gong, Tongyang, Fan, Dandan, Zhang, Ji, Chen, Fukun, Zhu, Xiaolin, Wang, Xinyu, Qiao, Yunbo, Chen, Hongyan, Liu, Zhihua, Su, Jianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358006/ https://www.ncbi.nlm.nih.gov/pubmed/34381055 http://dx.doi.org/10.1038/s41525-021-00232-6

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