Cargando…

ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer

Circulating tumor cell (CTC) clusters mediate metastasis at a higher efficiency and are associated with lower overall survival in breast cancer compared to single cells. Combining single-cell RNA sequencing and protein analyses, here we report the profiles of primary tumor cells and lung metastases...

Descripción completa

Detalles Bibliográficos
Autores principales:	Taftaf, Rokana, Liu, Xia, Singh, Salendra, Jia, Yuzhi, Dashzeveg, Nurmaa K., Hoffmann, Andrew D., El-Shennawy, Lamiaa, Ramos, Erika K., Adorno-Cruz, Valery, Schuster, Emma J., Scholten, David, Patel, Dhwani, Zhang, Youbin, Davis, Andrew A., Reduzzi, Carolina, Cao, Yue, D’Amico, Paolo, Shen, Yang, Cristofanilli, Massimo, Muller, William A., Varadan, Vinay, Liu, Huiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358026/ https://www.ncbi.nlm.nih.gov/pubmed/34381029 http://dx.doi.org/10.1038/s41467-021-25189-z

Ejemplares similares

EGFR inhibition blocks cancer stem cell clustering and lung metastasis of triple negative breast cancer
por: Liu, Xia, et al.
Publicado: (2021)

Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer
por: Dashzeveg, Nurmaa K., et al.
Publicado: (2023)

ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis
por: Adorno-Cruz, Valery, et al.
Publicado: (2020)

Machine learning-assisted elucidation of CD81–CD44 interactions in promoting cancer stemness and extracellular vesicle integrity
por: Ramos, Erika K, et al.
Publicado: (2022)

ICAM-1-suPAR-CD11b Axis Is a Novel Therapeutic Target for Metastatic Triple-Negative Breast Cancer
por: Li, Dong, et al.
Publicado: (2023)

Better together: circulating tumor cell clustering in metastatic cancer
por: Schuster, Emma, et al.
Publicado: (2021)

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients
por: Hoffmann, Andrew D., et al.
Publicado: (2023)

Single-Cells Isolation and Molecular Analysis: Focus on HER2-Low CTCs in Metastatic Breast Cancer
por: D’Amico, Paolo, et al.
Publicado: (2021)

Network-Based Enriched Gene Subnetwork Identification: A Game-Theoretic Approach
por: Razi, Abolfazl, et al.
Publicado: (2016)

Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer
por: Davis, Andrew A., et al.
Publicado: (2019)

Research productivity in Syria: Quantitative and qualitative analysis of current status
por: Diab, Maria M., et al.
Publicado: (2011)

PSAT017 A Case of Aldosterone- and Cortisol Co-secreting Adrenal Corticol Neoplasm with Lipomatous and Myeiolipomatous Metaplasia
por: Jinna, Sruthi, et al.
Publicado: (2022)

Aldosterone- and Cortisol Co-secreting Adrenal Cortical Neoplasm With Lipomatous and Myelolipomatous Metaplasia  
por: Jinna, Sruthi, et al.
Publicado: (2023)

Aneuploid CTC and CEC
por: Lin, Peter Ping
Publicado: (2018)

Evaluation of CO(2) emission from Egypt’s future power plants
por: Abdallah, Lamiaa, et al.
Publicado: (2020)

Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer
por: Reduzzi, Carolina, et al.
Publicado: (2021)

Magnetic Particles for CTC Enrichment
por: Liu, Peng, et al.
Publicado: (2020)

Recent Update Roles of Magnetic Nanoparticles in Circulating Tumor Cell (CTC)/Non-CTC Separation
por: Pipatwatcharadate, Chawapon, et al.
Publicado: (2023)

Premio literario CTC : Concurso Rubén Martínez Villena.
Publicado: (1976)

Circulating Tumor Cells (CTC) Are Associated with Defects in Adaptive Immunity in Patients with Inflammatory Breast Cancer
por: Mego, M, et al.
Publicado: (2016)

Benign Metastasizing Leiomyoma: A Rare Type of Lung Metastases—Two Case Reports and Review of the Literature
por: Taftaf, Rokana, et al.
Publicado: (2014)

ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo
por: Chong, Deborah L. W., et al.
Publicado: (2021)

ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients
por: Varadan, Vinay, et al.
Publicado: (2015)

Technical Challenges for CTC Implementation in Breast Cancer
por: Ramos-Medina, Rocío, et al.
Publicado: (2021)

EXTRACOLONIC FINDINGS—IDENTIFICATION AT LOW-DOSE CTC
por: Thorén, Fredrik, et al.
Publicado: (2021)

Mathematical Modelling for the Role of CD4(+)T Cells in Tumor-Immune Interactions
por: Makhlouf, Ahmed M., et al.
Publicado: (2020)

Effects of CTC(P) Modification on Microstructure and Wear Behavior of CTC(P)-NiCrBSi/Heat Resistant Steel Composite Layer
por: Zhang, Jianjun, et al.
Publicado: (2018)

May CTC technologies promote better cancer management?
por: Pesta, Martin, et al.
Publicado: (2015)

The Optimization of a Microfluidic CTC Filtering Chip by Simulation
por: Li, Huan, et al.
Publicado: (2017)

Characterization of the function of intercellular adhesion molecule (ICAM)-3 and comparison with ICAM-1 and ICAM-2 in immune responses
Publicado: (1994)

ATR cooperates with CTC1 and STN1 to maintain telomeres and genome integrity in Arabidopsis
por: Boltz, Kara A., et al.
Publicado: (2012)

MARCH8 Suppresses Tumor Metastasis and Mediates Degradation of STAT3 and CD44 in Breast Cancer Cells
por: Chen, Wenjing, et al.
Publicado: (2021)

Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
por: El-Shennawy, Lamiaa, et al.
Publicado: (2022)

Molecular basis of telomere syndrome caused by CTC1 mutations
por: Chen, Liuh-Yow, et al.
Publicado: (2013)

The isolation and characterization of CTC subsets related to breast cancer dormancy
por: Vishnoi, Monika, et al.
Publicado: (2015)

Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis
por: de Wit, Sanne, et al.
Publicado: (2018)

Optimal Halbach Configuration for Flow-through Immunomagnetic CTC Enrichment
por: Stevens, Michiel, et al.
Publicado: (2021)

Implementation of an Integrated Dielectrophoretic and Magnetophoretic Microfluidic Chip for CTC Isolation
por: Zhao, Kai, et al.
Publicado: (2022)

Improving 2-Chlorotrityl Chloride (2-CTC) Resin Activation
por: Román, Tanya, et al.
Publicado: (2023)

CTC, ctDNA, and Exosome in Thyroid Cancers: A Review
por: Wang, Wenwen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m8ikas2he9rgijk5gpo3nqlj4e