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Listeria monocytogenes-infected human monocytic derived dendritic cells activate Vγ9Vδ2 T cells independently of HMBPP production

Gamma-delta (γδ) T cells express T cell receptors (TCR) that are preconfigured to recognize signs of pathogen infection. In primates, γδ T cells expressing the Vγ9Vδ2 TCR innately recognize (E)-4-hydroxy-3-methyl-but- 2-enyl pyrophosphate (HMBPP), a product of the 2-C-methyl-D-erythritol 4- phosphat...

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Detalles Bibliográficos
Autores principales:	Alice, Alejandro F., Kramer, Gwen, Bambina, Shelly, Bahjat, Keith S., Gough, Michael J., Crittenden, Marka R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358051/ https://www.ncbi.nlm.nih.gov/pubmed/34381163 http://dx.doi.org/10.1038/s41598-021-95908-5

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