Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation

Pediatric gliomas comprise a broad range of brain tumors derived from glial cells. While high-grade gliomas are often resistant to therapy and associated with a poor outcome, children with low-grade gliomas face a better prognosis. However, the treatment of low-grade gliomas is often associated with...

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Detalles Bibliográficos
Autores principales: Meier, Stefanie, Cantilena, Sandra, Niklison Chirou, Maria Victoria, Anderson, John, Hargrave, Darren, Salomoni, Paolo, de Boer, Jasper, Michod, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358054/
https://www.ncbi.nlm.nih.gov/pubmed/34381018
http://dx.doi.org/10.1038/s41419-021-04078-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358054/
https://www.ncbi.nlm.nih.gov/pubmed/34381018
http://dx.doi.org/10.1038/s41419-021-04078-9

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