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Stochastic probical strategies in a delay virus infection model to combat COVID-19
In disease model systems, random noises and time delay factors play key role in interpreting disease dynamics to comprehend deeper insights into the course of dynamics. An endeavor to forecast intercellular behavioral dynamics of SARS-CoV-2 virus via Infection model with responsive host immune mecha...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358091/ https://www.ncbi.nlm.nih.gov/pubmed/34400855 http://dx.doi.org/10.1016/j.chaos.2021.111325 |
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author | Pitchaimani, M. Brasanna Devi, M. |
author_facet | Pitchaimani, M. Brasanna Devi, M. |
author_sort | Pitchaimani, M. |
collection | PubMed |
description | In disease model systems, random noises and time delay factors play key role in interpreting disease dynamics to comprehend deeper insights into the course of dynamics. An endeavor to forecast intercellular behavioral dynamics of SARS-CoV-2 virus via Infection model with responsive host immune mechanisms forms the crux of this research study. Incorporation of time delay factor into infection transmission rates in noisy system epitomizes spectacular view on internal viral dynamics and stability properties are rigorously analyzed around equilibrium steady states to probe feasible strategies in mitigating rapid spread. Efforts to perceive inocular view on infection dynamics are not limited to theoretical frontiers but are substantiated with empirically simulated outcomes and visualized as graphical upshots. Discussions on numerical investigations emphasized shorter incubation periods and vaccination at pertinent time intervals to restrain massive spread and exhibit total immunity against SARS-CoV-2 infections. |
format | Online Article Text |
id | pubmed-8358091 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83580912021-08-12 Stochastic probical strategies in a delay virus infection model to combat COVID-19 Pitchaimani, M. Brasanna Devi, M. Chaos Solitons Fractals Article In disease model systems, random noises and time delay factors play key role in interpreting disease dynamics to comprehend deeper insights into the course of dynamics. An endeavor to forecast intercellular behavioral dynamics of SARS-CoV-2 virus via Infection model with responsive host immune mechanisms forms the crux of this research study. Incorporation of time delay factor into infection transmission rates in noisy system epitomizes spectacular view on internal viral dynamics and stability properties are rigorously analyzed around equilibrium steady states to probe feasible strategies in mitigating rapid spread. Efforts to perceive inocular view on infection dynamics are not limited to theoretical frontiers but are substantiated with empirically simulated outcomes and visualized as graphical upshots. Discussions on numerical investigations emphasized shorter incubation periods and vaccination at pertinent time intervals to restrain massive spread and exhibit total immunity against SARS-CoV-2 infections. Elsevier Ltd. 2021-11 2021-08-12 /pmc/articles/PMC8358091/ /pubmed/34400855 http://dx.doi.org/10.1016/j.chaos.2021.111325 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Pitchaimani, M. Brasanna Devi, M. Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title | Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title_full | Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title_fullStr | Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title_full_unstemmed | Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title_short | Stochastic probical strategies in a delay virus infection model to combat COVID-19 |
title_sort | stochastic probical strategies in a delay virus infection model to combat covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358091/ https://www.ncbi.nlm.nih.gov/pubmed/34400855 http://dx.doi.org/10.1016/j.chaos.2021.111325 |
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