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Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties

The human apolipoprotein L gene family encodes the apolipoprotein L1–6 (APOL1–6) proteins, which are effectors of the innate immune response to viruses, bacteria and protozoan parasites. Due to a high degree of similarity between APOL proteins, it is often assumed that they have similar functions to...

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Detalles Bibliográficos
Autores principales: Pant, Jyoti, Giovinazzo, Joseph A., Tuka, Lilit S., Peña, Darwin, Raper, Jayne, Thomson, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358165/
https://www.ncbi.nlm.nih.gov/pubmed/34252458
http://dx.doi.org/10.1016/j.jbc.2021.100951

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