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Apolipoproteins L1-6 share key cation channel-regulating residues but have different membrane insertion and ion conductance properties
The human apolipoprotein L gene family encodes the apolipoprotein L1–6 (APOL1–6) proteins, which are effectors of the innate immune response to viruses, bacteria and protozoan parasites. Due to a high degree of similarity between APOL proteins, it is often assumed that they have similar functions to...
Autores principales: | Pant, Jyoti, Giovinazzo, Joseph A., Tuka, Lilit S., Peña, Darwin, Raper, Jayne, Thomson, Russell |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358165/ https://www.ncbi.nlm.nih.gov/pubmed/34252458 http://dx.doi.org/10.1016/j.jbc.2021.100951 |
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