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Sustained response to brigatinib in a patient with refractory metastatic pheochromocytoma harboring R1192P anaplastic lymphoma kinase mutation: a case report from the Austrian Group Medical Tumor Therapy next-generation sequencing registry and discussion of the literature
Metastatic pheochromocytoma and paraganglioma (PPGL) are rare diseases with dismal prognosis and standard therapies are lacking. We herein report the first case of a germline anaplastic lymphoma kinase (ALK) mutation in a patient with chemorefractory metastatic pheochromocytoma in the absence of mut...
Autores principales: | Heregger, R., Huemer, F., Hutarew, G., Hecht, S., Cheveresan, L., Kotzot, D., Schamschula, E., Rinnerthaler, G., Melchardt, T., Weiss, L., Greil, R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358412/ https://www.ncbi.nlm.nih.gov/pubmed/34371380 http://dx.doi.org/10.1016/j.esmoop.2021.100233 |
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