Impact of deleterious variants in other genes beyond BRCA1/2 detected in breast/ovarian and pancreatic cancer patients by NGS-based multi-gene panel testing: looking over the hedge

BACKGROUND: Hereditary breast cancer (BC), ovarian cancer (OC), and pancreatic cancer (PC) are the major BRCA-associated tumours. However, some BRCA1/2-wild-type (wt) patients with a strong personal and/or family history of cancer need a further genetic testing through a multi-gene panel containing...

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Detalles Bibliográficos
Autores principales: Bono, M., Fanale, D., Incorvaia, L., Cancelliere, D., Fiorino, A., Calò, V., Dimino, A., Filorizzo, C., Corsini, L.R., Brando, C., Madonia, G., Cucinella, A., Scalia, R., Barraco, N., Guadagni, F., Pedone, E., Badalamenti, G., Russo, A., Bazan, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358413/
https://www.ncbi.nlm.nih.gov/pubmed/34371384
http://dx.doi.org/10.1016/j.esmoop.2021.100235

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