Recombinant High-Mobility Group Box 1 (rHMGB1) Promotes NRF2-Independent Mitochondrial Fusion through CXCR4/PSMB5-Mediated Drp1 Degradation in Endothelial Cells

Mitochondrial dynamics plays an important role in maintaining normal endothelial cell function and in the pathogenesis of cardiovascular disease. It is not identified whether high-mobility group box 1 (HMGB1), a representative damage-associated molecular pattern (DAMP) molecule, could influence mito...

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Detalles Bibliográficos
Autores principales: Zhang, Shunrong, Feng, Fei, Dai, Jingting, Li, Jia, Bu, Xiangye, Xie, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358426/
https://www.ncbi.nlm.nih.gov/pubmed/34394840
http://dx.doi.org/10.1155/2021/9993240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358426/
https://www.ncbi.nlm.nih.gov/pubmed/34394840
http://dx.doi.org/10.1155/2021/9993240

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