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Brucella spp. Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production

Type I interferons (IFN), a family of cytokines widely expressed in various tissues, play important roles in anti-infection immunity. Nevertheless, it is not known whether Brucella spp. could interfere with IFN-I production induced by other pathogens. This study investigated the regulatory roles of...

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Detalles Bibliográficos
Autores principales:	Li, Ruizhen, Liu, Wenli, Yin, Xiangrui, Zheng, Fangfang, Wang, Zhenyu, Wu, Xingchen, Zhang, Xiaohua, Du, Qian, Huang, Yong, Tong, Dewen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358459/ https://www.ncbi.nlm.nih.gov/pubmed/34394047 http://dx.doi.org/10.3389/fmicb.2021.702881

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