Sphingomyelinase decreases transepithelial anion secretion in airway epithelial cells in part by inhibiting CFTR‐mediated apical conductance

The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel whose dysfunction causes cystic fibrosis (CF). The loss of CFTR function in pulmonary epithelial cells causes surface dehydration, mucus build‐up, inflammation, and bacterial infections that lead to lung failure. Litt...

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Detalles Bibliográficos
Autores principales: Cottrill, Kirsten A., Peterson, Raven J., Lewallen, Colby F., Koval, Michael, Bridges, Robert J., McCarty, Nael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358481/
https://www.ncbi.nlm.nih.gov/pubmed/34382377
http://dx.doi.org/10.14814/phy2.14928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358481/
https://www.ncbi.nlm.nih.gov/pubmed/34382377
http://dx.doi.org/10.14814/phy2.14928

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