Differences in the placental pharmacokinetics of vedolizumab and ustekinumab during pregnancy in women with inflammatory bowel disease: a prospective multicentre study

BACKGROUND: Vedolizumab demonstrated different placental pharmacokinetics than other immunoglobulin G1 antibodies, leading to lower drug levels in cord blood in contrast to maternal blood at the time of delivery. The placental transfer of ustekinumab seems to have a pattern similar to anti-tumour ne...

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Detalles Bibliográficos
Autores principales: Mitrova, Katarina, Pipek, Barbora, Bortlik, Martin, Bouchner, Ludek, Brezina, Jan, Douda, Tomas, Drasar, Tomas, Drastich, Pavel, Falt, Premysl, Klvana, Pavel, Leksa, Vaclav, Novotny, Ales, Svoboda, Pavel, Skorpik, Jan, Ulbrych, Jan, Veinfurt, Marek, Zborilova, Blanka, Lukas, Milan, Duricova, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358502/
https://www.ncbi.nlm.nih.gov/pubmed/34394725
http://dx.doi.org/10.1177/17562848211032790

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