Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization

• ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization. • ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure.

Detalles Bibliográficos
Autores principales: Ho, Idy H.T., Ng, Lhotse H.L., Cheng, Xiaojie, Gin, Tony, Chan, Chee Sam, Sun, Wuping, Xiao, Lizu, Zhang, Lin, Chan, Matthew T.V., Wu, William K.K., Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358694/
https://www.ncbi.nlm.nih.gov/pubmed/34401608
http://dx.doi.org/10.1016/j.ynpai.2021.100071
Descripción
Sumario:• ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization. • ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure.

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