Cargando…

Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization

• ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization. • ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure.

Detalles Bibliográficos
Autores principales: Ho, Idy H.T., Ng, Lhotse H.L., Cheng, Xiaojie, Gin, Tony, Chan, Chee Sam, Sun, Wuping, Xiao, Lizu, Zhang, Lin, Chan, Matthew T.V., Wu, William K.K., Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358694/
https://www.ncbi.nlm.nih.gov/pubmed/34401608
http://dx.doi.org/10.1016/j.ynpai.2021.100071
_version_ 1783737396664205312
author Ho, Idy H.T.
Ng, Lhotse H.L.
Cheng, Xiaojie
Gin, Tony
Chan, Chee Sam
Sun, Wuping
Xiao, Lizu
Zhang, Lin
Chan, Matthew T.V.
Wu, William K.K.
Liu, Xiaodong
author_facet Ho, Idy H.T.
Ng, Lhotse H.L.
Cheng, Xiaojie
Gin, Tony
Chan, Chee Sam
Sun, Wuping
Xiao, Lizu
Zhang, Lin
Chan, Matthew T.V.
Wu, William K.K.
Liu, Xiaodong
author_sort Ho, Idy H.T.
collection PubMed
description • ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization. • ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure.
format Online
Article
Text
id pubmed-8358694
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83586942021-08-15 Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization Ho, Idy H.T. Ng, Lhotse H.L. Cheng, Xiaojie Gin, Tony Chan, Chee Sam Sun, Wuping Xiao, Lizu Zhang, Lin Chan, Matthew T.V. Wu, William K.K. Liu, Xiaodong Neurobiol Pain Original Research • ANXA2 is a novel MOR1-interacting protein regulating MOR1 sub-cellular localization. • ANXA2 retains MOR1 in late recycling endosomes after remifentanil exposure. Elsevier 2021-08-02 /pmc/articles/PMC8358694/ /pubmed/34401608 http://dx.doi.org/10.1016/j.ynpai.2021.100071 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Research
Ho, Idy H.T.
Ng, Lhotse H.L.
Cheng, Xiaojie
Gin, Tony
Chan, Chee Sam
Sun, Wuping
Xiao, Lizu
Zhang, Lin
Chan, Matthew T.V.
Wu, William K.K.
Liu, Xiaodong
Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title_full Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title_fullStr Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title_full_unstemmed Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title_short Annexin A2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
title_sort annexin a2 traps mu-opioid receptors in recycling endosomes upon remifentanil-induced internalization
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358694/
https://www.ncbi.nlm.nih.gov/pubmed/34401608
http://dx.doi.org/10.1016/j.ynpai.2021.100071
work_keys_str_mv AT hoidyht annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT nglhotsehl annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT chengxiaojie annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT gintony annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT chancheesam annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT sunwuping annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT xiaolizu annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT zhanglin annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT chanmatthewtv annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT wuwilliamkk annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization
AT liuxiaodong annexina2trapsmuopioidreceptorsinrecyclingendosomesuponremifentanilinducedinternalization