Regulation of CTLA‐4 recycling by LRBA and Rab11

CTLA‐4 is an essential regulator of T‐cell immune responses whose intracellular trafficking is a hallmark of its expression. Defects in CTLA‐4 trafficking due to LRBA deficiency cause profound autoimmunity in humans. CTLA‐4 rapidly internalizes via a clathrin‐dependent pathway followed by poorly cha...

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Detalles Bibliográficos
Autores principales: Janman, Daniel, Hinze, Claudia, Kennedy, Alan, Halliday, Neil, Waters, Erin, Williams, Cayman, Rowshanravan, Behzad, Hou, Tie Zheng, Minogue, Shane, Qureshi, Omar S., Sansom, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358724/
https://www.ncbi.nlm.nih.gov/pubmed/33960403
http://dx.doi.org/10.1111/imm.13343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358724/
https://www.ncbi.nlm.nih.gov/pubmed/33960403
http://dx.doi.org/10.1111/imm.13343

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