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Modified recombinant human IgG1‐Fc is superior to natural intravenous immunoglobulin at inhibiting immune‐mediated demyelination

Intravenous immunoglobulin (IVIG) is an established treatment for numerous autoimmune conditions. Although Fc fragments derived from IVIG have shown efficacy in controlling immune thrombocytopenia in children, the mechanisms of action are unclear and controversial. The aim of this study was to disse...

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Detalles Bibliográficos
Autores principales: Baksmeier, Christine, Blundell, Pat, Steckel, Julia, Schultz, Verena, Gu, Quan, Da Silva Filipe, Ana, Kohl, Alain, Linnington, Chris, Lu, Dongli, Dell, Anne, Haslam, Stuart, Wang, Jiabin, Czajkowsky, Dan, Goebels, Norbert, Pleass, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358725/
https://www.ncbi.nlm.nih.gov/pubmed/33880776
http://dx.doi.org/10.1111/imm.13341