Cargando…

GVHD Pathogenesis, Prevention and Treatment: Lessons From Humanized Mouse Transplant Models

Graft-vs-host disease (GVHD) is the most common cause of non-relapse mortality following allogeneic hematopoietic stem cell transplantation (HSCT) despite advances in conditioning regimens, HLA genotyping and immune suppression. While murine studies have yielded important insights into the cellular...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hess, Nicholas J., Brown, Matthew E., Capitini, Christian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358790/ https://www.ncbi.nlm.nih.gov/pubmed/34394131 http://dx.doi.org/10.3389/fimmu.2021.723544

Ejemplares similares

Exosomes, MDSCs and Tregs: A new frontier for GVHD prevention and treatment
por: Hess, Nicholas J., et al.
Publicado: (2023)

Current Preventions and Treatments of aGVHD: From Pharmacological Prophylaxis to Innovative Therapies
por: Naserian, Sina, et al.
Publicado: (2020)

GVHD Prophylaxis 2020
por: Gooptu, Mahasweta, et al.
Publicado: (2021)

Controversies and expectations for the prevention of GVHD: A biological and clinical perspective
por: Watkins, Benjamin, et al.
Publicado: (2022)

Established and Emerging Treatments of Skin GvHD
por: Link-Rachner, Cornelia S., et al.
Publicado: (2022)

Editorial: Novel and Improved Methods for the Prevention and Treatment of Graft-Versus-Host Disease (GVHD)
por: Ullrich, Evelyn, et al.
Publicado: (2022)

Donor T-Cell Repertoire Profiling in Recipient Lymphoid and Parenchyma Organs Reveals GVHD Pathogenesis at Clonal Levels After Bone Marrow Transplantation in Mice
por: Wu, Yongxia, et al.
Publicado: (2021)

Bone Marrow GvHD after Allogeneic Hematopoietic Stem Cell Transplantation
por: Szyska, Martin, et al.
Publicado: (2016)

The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview
por: Boieri, Margherita, et al.
Publicado: (2016)

Editorial: Interferons and GvHD
por: Kim, Boram, et al.
Publicado: (2022)

Regulatory T Cells in GVHD Therapy
por: Guo, Wen-wen, et al.
Publicado: (2021)

Milestones in acute GVHD pathophysiology
por: Socie, Gerard, et al.
Publicado: (2022)

Interleukin-6 as Biomarker for Acute GvHD and Survival After Allogeneic Transplant With Post-transplant Cyclophosphamide
por: Greco, Raffaella, et al.
Publicado: (2019)

Impact of oral microbiota on pathophysiology of GVHD
por: Yamamoto, Akira, et al.
Publicado: (2023)

Intestinal Microbiota Influence Immune Tolerance Post Allogeneic Hematopoietic Cell Transplantation and Intestinal GVHD
por: Köhler, Natalie, et al.
Publicado: (2019)

ER stress: an emerging regulator in GVHD development
por: Choi, Hee-Jin, et al.
Publicado: (2023)

Relation between Acute GVHD and NK Cell Subset Reconstitution Following Allogeneic Stem Cell Transplantation
por: Ullrich, Evelyn, et al.
Publicado: (2016)

Donor γδT Cells Promote GVL Effect and Mitigate aGVHD in Allogeneic Hematopoietic Stem Cell Transplantation
por: Song, Yuan, et al.
Publicado: (2020)

Novel Insights Into the Mechanism of GVHD-Induced Tissue Damage
por: Ara, Takahide, et al.
Publicado: (2021)

Developing role of B cells in the pathogenesis and treatment of chronic GVHD
por: Li, Xiaoping, et al.
Publicado: (2018)

Extracorporeal photopheresis as an immunomodulatory treatment modality for chronic GvHD and the importance of emerging biomarkers
por: Bojanic, Ines, et al.
Publicado: (2023)

Humanized Mouse Models for the Study of Human Malaria Parasite Biology, Pathogenesis, and Immunity
por: Minkah, Nana K., et al.
Publicado: (2018)

Pathophysiology of GvHD and Other HSCT-Related Major Complications
por: Ghimire, Sakhila, et al.
Publicado: (2017)

Tolerance to Bone Marrow Transplantation: Do Mesenchymal Stromal Cells Still Have a Future for Acute or Chronic GvHD?
por: Introna, Martino, et al.
Publicado: (2020)

Case report: Rare persistent complete donor chimerism and GVHD following micro-transplantation from HLA haplotype homozygous donors
por: Liu, Lingling, et al.
Publicado: (2022)

Impaired thymic iNKT cell differentiation at early precursor stage in murine haploidentical bone marrow transplantation with GvHD
por: Zhao, Weijia, et al.
Publicado: (2023)

Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology
por: Hess, Nicholas J., et al.
Publicado: (2023)

Lower dose of ATG combined with basiliximab for haploidentical hematopoietic stem cell transplantation is associated with effective control of GVHD and less CMV viremia
por: Huang, Zhenli, et al.
Publicado: (2022)

Cyclosporine A but Not Corticosteroids Support Efficacy of Ex Vivo Expanded, Adoptively Transferred Human Tregs in GvHD
por: Landwehr-Kenzel, Sybille, et al.
Publicado: (2021)

Editorial on Translational Research in Graft-Versus-Host Disease (GVHD) and Graft-Versus-Tumor (GVT) Effect After Allogeneic Hematopoietic Cell Transplantation
por: Czech, Marie, et al.
Publicado: (2022)

Pre-transplant CD69+ extracellular vesicles are negatively correlated with active ATLG serum levels and associate with the onset of GVHD in allogeneic HSCT patients
por: Storci, Gianluca, et al.
Publicado: (2023)

The Effects of Interferons on Allogeneic T Cell Response in GVHD: The Multifaced Biology and Epigenetic Regulations
por: Zhao, Chenchen, et al.
Publicado: (2021)

Advances in Humanized Mouse Models to Improve Understanding of HIV-1 Pathogenesis and Immune Responses
por: Gillgrass, Amy, et al.
Publicado: (2021)

Progress in construction of mouse models to investigate the pathogenesis and immune therapy of human hematological malignancy
por: Lang, Yue, et al.
Publicado: (2023)

Mouse Models to Study Dengue Virus Immunology and Pathogenesis
por: Zellweger, Raphaël M., et al.
Publicado: (2014)

Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity
por: Song, Qingxiao, et al.
Publicado: (2022)

Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival
por: Kordelas, Lambros, et al.
Publicado: (2021)

Case Report: Combination Therapy With PD-1 Blockade for Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation Resulted in Fatal GVHD
por: Yao, Sun, et al.
Publicado: (2021)

Safety and Efficacy of Fecal Microbiota Transplantation for Grade IV Steroid Refractory GI-GvHD Patients: Interim Results From FMT2017002 Trial
por: Zhao, Ye, et al.
Publicado: (2021)

Low-dose decitabine-intensified modified conditioning regimen alleviates aGVHD in AML/MDS patients treated with allogeneic hematopoietic stem cell transplantation
por: Zhu, Jinye, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hgujk4ke8k2uv7rs3oirt98r97