The alternative serotonin transporter promoter P2 impacts gene function in females with irritable bowel syndrome

Irritable bowel syndrome (IBS) is a gut‐brain disorder in which symptoms are shaped by serotonin acting centrally and peripherally. The serotonin transporter gene SLC6A4 has been implicated in IBS pathophysiology, but the underlying genetic mechanisms remain unclear. We sequenced the alternative P2...

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Detalles Bibliográficos
Autores principales: Mohr, Sandra, Fritz, Nikola, Hammer, Christian, Martínez, Cristina, Berens, Sabrina, Schmitteckert, Stefanie, Wahl, Verena, Schmidt, Malin, Houghton, Lesley A., Goebel‐Stengel, Miriam, Kabisch, Maria, Götze, Dorothea, Milovač, Irina, D’Amato, Mauro, Zheng, Tenghao, Röth, Ralph, Mönnikes, Hubert, Engel, Felicitas, Gauss, Annika, Tesarz, Jonas, Raithel, Martin, Andresen, Viola, Frieling, Thomas, Keller, Jutta, Pehl, Christian, Stein‐Thöringer, Christoph, Clarke, Gerard, Kennedy, Paul J., Cryan, John F., Dinan, Timothy G., Quigley, Eamonn M. M., Spiller, Robin, Beltrán, Caroll, Madrid, Ana María, Torres, Verónica, Pérez de Arce, Edith, Herzog, Wolfgang, Mayer, Emeran A., Sayuk, Gregory, Gazouli, Maria, Karamanolis, George, Kapur‐Pojskič, Lejla, Bustamante, Mariona, Rabionet, Raquel, Estivil, Xavier, Franke, André, Lieb, Wolfgang, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Rappold, Gudrun A., Vicario, Maria, Santos, Javier, Schaefert, Rainer, Lorenzo‐Bermejo, Justo, Niesler, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358858/
https://www.ncbi.nlm.nih.gov/pubmed/34165249
http://dx.doi.org/10.1111/jcmm.16736

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