CXCL12/CXCR4 facilitates perineural invasion via induction of the Twist/S100A4 axis in salivary adenoid cystic carcinoma

The activation of CXCL12/CXCR4 axis participated in the progression of multiple cancers, but potential effect in terms of perineural invasion (PNI) in SACC remained ambiguous. In this study, we identified that CXCL12 substantially expressed in nerve cells. CXCR4 strikingly expressed in tumour cells,...

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Detalles Bibliográficos
Autores principales: Zhang, Mei, Zheng, Min, Dai, Li, Zhang, Wei‐long, Fan, Hua‐yang, Yu, Xiang‐hua, Pang, Xin, Liao, Peng, Chen, Bing‐jun, Wang, Sha‐sha, Cao, Ming‐xin, Ma, Xiang‐rui, Liang, Xin‐hua, Tang, Ya‐ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358865/
https://www.ncbi.nlm.nih.gov/pubmed/34170080
http://dx.doi.org/10.1111/jcmm.16713

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