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EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells
Irinotecan is a kind of alkaloid with antitumour activity, but its low solubility and high toxicity limit its application. Epigallocatechin‐3‐gallate (EGCG) is one of the main bioactive components in tea. The epidemiological investigation and animal and cell experiments show that EGCG has a preventi...
Autores principales: | Wu, Wenbing, Dong, Jingying, Gou, Hui, Geng, Ruiman, Yang, Xiaolong, Chen, Dan, Xiang, Bin, Zhang, Zhengkun, Ren, Sichong, Chen, Lihong, Liu, Ji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358867/ https://www.ncbi.nlm.nih.gov/pubmed/34132471 http://dx.doi.org/10.1111/jcmm.16718 |
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