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EGCG synergizes the therapeutic effect of irinotecan through enhanced DNA damage in human colorectal cancer cells

Irinotecan is a kind of alkaloid with antitumour activity, but its low solubility and high toxicity limit its application. Epigallocatechin‐3‐gallate (EGCG) is one of the main bioactive components in tea. The epidemiological investigation and animal and cell experiments show that EGCG has a preventi...

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Detalles Bibliográficos
Autores principales: Wu, Wenbing, Dong, Jingying, Gou, Hui, Geng, Ruiman, Yang, Xiaolong, Chen, Dan, Xiang, Bin, Zhang, Zhengkun, Ren, Sichong, Chen, Lihong, Liu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358867/
https://www.ncbi.nlm.nih.gov/pubmed/34132471
http://dx.doi.org/10.1111/jcmm.16718

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