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METTL3/N6‐methyladenosine/ miR‐21‐5p promotes obstructive renal fibrosis by regulating inflammation through SPRY1/ERK/NF‐κB pathway activation
Renal fibrosis induced by urinary tract obstruction is a common clinical occurrence; however, effective treatment is lacking, and a deeper understanding of the mechanism of renal fibrosis is needed. Previous studies have revealed that miR‐21 impacts liver and lung fibrosis progression by activating...
Autores principales: | Liu, Erpeng, Lv, Lei, Zhan, Yonghao, Ma, Yuan, Feng, Jinjin, He, Yulin, Wen, Yibo, Zhang, Yanping, Pu, Qingsong, Ji, Fengping, Yang, Xinghuan, Wen, Jian Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8358893/ https://www.ncbi.nlm.nih.gov/pubmed/34164910 http://dx.doi.org/10.1111/jcmm.16603 |
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