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Intranasal immunization with O-2′-Hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles loaded with Newcastle disease virus DNA vaccine enhances mucosal immune response in chickens

BACKGROUND: There has been a great interest in developing strategies for enhancing antigen delivery to the mucosal immune system as well as identifying mucosal active immunostimulating agents. To elevate the potential of O-2ʹ-Hydroxypropyl trimethyl ammonium chloride chitosan (O-2ʹ-HACC) as an adjuv...

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Detalles Bibliográficos
Autores principales:	Zhao, Kai, Sun, Beini, Shi, Ci, Sun, Yanwei, Jin, Zheng, Hu, Gaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359106/ https://www.ncbi.nlm.nih.gov/pubmed/34380522 http://dx.doi.org/10.1186/s12951-021-00983-5

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