Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases

BACKGROUND: Phosphorylcholine (PC) is an important pro‐inflammatory damage‐associated molecular pattern. Previous data have shown that natural IgM anti‐PC protects against cardiovascular disease. We aimed to develop a monoclonal PC IgG antibody with anti‐inflammatory and anti‐atherosclerotic propert...

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Detalles Bibliográficos
Autores principales: de Vries, M. R., Ewing, M. M., de Jong, R. C. M., MacArthur, M. R., Karper, J. C., Peters, E. A. B., Nordzell, M., Karabina, S. A. P., Sexton, D., Dahlbom, I., Bergman, A., Mitchell, J. R., Frostegård, J., Kuiper, J., Ninio, E., Jukema, J. W., Pettersson, K., Quax, P. H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359267/
https://www.ncbi.nlm.nih.gov/pubmed/33342002
http://dx.doi.org/10.1111/joim.13234

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