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Population pharmacokinetics of clofarabine for allogeneic hematopoietic cell transplantation in paediatric patients

AIMS: Clofarabine has recently been evaluated as part of the conditioning regimen for allogeneic hematopoietic stem cell transplantation (HCT) in children. Pharmacokinetic (PK) exposure of different agents commonly used in conditioning regimens is strongly related to HCT outcome. Consequently, the P...

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Detalles Bibliográficos
Autores principales: Nijstad, A. Laura, Nierkens, Stefan, Lindemans, Caroline A., Boelens, Jaap Jan, Bierings, Marc, Versluys, A. Birgitta, van der Elst, Kim C.M., Huitema, Alwin D.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359279/
https://www.ncbi.nlm.nih.gov/pubmed/33444472
http://dx.doi.org/10.1111/bcp.14738

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