A novel statistical method for modeling covariate effects in bisulfite sequencing derived measures of DNA methylation

Identifying disease‐associated changes in DNA methylation can help us gain a better understanding of disease etiology. Bisulfite sequencing allows the generation of high‐throughput methylation profiles at single‐base resolution of DNA. However, optimally modeling and analyzing these sparse and discr...

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Detalles Bibliográficos
Autores principales: Zhao, Kaiqiong, Oualkacha, Karim, Lakhal‐Chaieb, Lajmi, Labbe, Aurélie, Klein, Kathleen, Ciampi, Antonio, Hudson, Marie, Colmegna, Inés, Pastinen, Tomi, Zhang, Tieyuan, Daley, Denise, Greenwood, Celia M.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Biometric Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359306/
https://www.ncbi.nlm.nih.gov/pubmed/32438470
http://dx.doi.org/10.1111/biom.13307

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