The ratio of ursodeoxycholyltaurine to 7‐oxolithocholyltaurine serves as a biomarker of decreased 11β‐hydroxysteroid dehydrogenase 1 activity in mouse

BACKGROUND AND PURPOSE: 11β‐Hydroxysteroid dehydrogenase 1 (11β‐HSD1) regulates tissue‐specific glucocorticoid metabolism and its impaired expression and activity are associated with major diseases. Pharmacological inhibition of 11β‐HSD1 is considered a promising therapeutic strategy. This study inv...

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Detalles Bibliográficos
Autores principales: Weingartner, Michael, Stücheli, Simon, Kratschmar, Denise V., Birk, Julia, Klusonova, Petra, Chapman, Karen E., Lavery, Gareth G., Odermatt, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Oxysterols, Lifelong Health and Therapeutics–Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359391/
https://www.ncbi.nlm.nih.gov/pubmed/33450045
http://dx.doi.org/10.1111/bph.15367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359391/
https://www.ncbi.nlm.nih.gov/pubmed/33450045
http://dx.doi.org/10.1111/bph.15367

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