Pharmacological validation of TDO as a target for Parkinson’s disease

Parkinson’s disease patients suffer from both motor and nonmotor impairments. There is currently no cure for Parkinson’s disease, and the most commonly used treatment, levodopa, only functions as a temporary relief of motor symptoms. Inhibition of the expression of the L‐tryptophan‐catabolizing enzy...

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Detalles Bibliográficos
Autores principales: Perez‐Pardo, Paula, Grobben, Yvonne, Willemsen‐Seegers, Nicole, Hartog, Mitch, Tutone, Michaela, Muller, Michelle, Adolfs, Youri, Pasterkamp, Ronald Jeroen, Vu‐Pham, Diep, van Doornmalen, Antoon M., van Cauter, Freek, de Wit, Joeri, Gerard Sterrenburg, Jan, Uitdehaag, Joost C.M., de Man, Jos, Buijsman, Rogier C., Zaman, Guido J.R., Kraneveld, Aletta D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359396/
https://www.ncbi.nlm.nih.gov/pubmed/33471408
http://dx.doi.org/10.1111/febs.15721

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