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Identifying predictors of response to oral non-steroidal anti-inflammatory drugs and paracetamol in osteoarthritis: a hypothesis-driven protocol for an OA Trial Bank individual participant data meta-analysis

INTRODUCTION: Symptomatic treatments for osteoarthritis (OA) provide only small-to-moderate efficacy over placebo in randomised controlled trials (RCTs). Treatment guidelines therefore have emphasised the need to identify predictors of treatment response through subgroup and multiple regression anal...

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Detalles Bibliográficos
Autores principales: Xiong, Yilin, Zeng, Chao, Doherty, Michael, Persson, Monica S M, Wei, Jie, van Middelkoop, Marienke, Lei, Guanghua, Zhang, Weiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359469/
https://www.ncbi.nlm.nih.gov/pubmed/34380727
http://dx.doi.org/10.1136/bmjopen-2021-048652