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Detection of intracranial hypertension in children using optical coherence tomography: a systematic review

OBJECTIVES: To evaluate the diagnostic capability of optical coherence tomography (OCT) in children aged under 18 years old with intracranial hypertension (IH). DESIGN: Systematic review. METHODS: We conducted a systematic review using the following platforms to search the keywords ‘optical coherenc...

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Autores principales: Rufai, Sohaib R, Hisaund, Michael, Jeelani, Noor ul Owase, McLean, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359522/
https://www.ncbi.nlm.nih.gov/pubmed/34380720
http://dx.doi.org/10.1136/bmjopen-2020-046935
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author Rufai, Sohaib R
Hisaund, Michael
Jeelani, Noor ul Owase
McLean, Rebecca J
author_facet Rufai, Sohaib R
Hisaund, Michael
Jeelani, Noor ul Owase
McLean, Rebecca J
author_sort Rufai, Sohaib R
collection PubMed
description OBJECTIVES: To evaluate the diagnostic capability of optical coherence tomography (OCT) in children aged under 18 years old with intracranial hypertension (IH). DESIGN: Systematic review. METHODS: We conducted a systematic review using the following platforms to search the keywords ‘optical coherence tomography’ and ‘intracranial hypertension’ from inception to 2 April 2020: Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, PubMed and Web of Science, without language restrictions. Our search returned 2729 records, screened by two independent screeners. Studies were graded according to the Oxford Centre for Evidence-Based Medicine and National Institutes of Health Quality Assessment Tool for observational studies. RESULTS: Twenty-one studies were included. Conditions included craniosynostosis (n=354 patients), idiopathic IH (IIH; n=102), space-occupying lesion (SOL; n=42) and other pathology (n=29). OCT measures included optic nerve parameters, rim parameters (notably retinal nerve fibre layer thickness) and retinal parameters. Levels of evidence included 2b (n=13 studies), 3b (n=4) and 4 (n=4). Quality of 10 studies was fair and 11 poor. There was inconsistency in OCT parameters and reference measures studied, although OCT did demonstrate good diagnostic capability for IH in craniosynostosis, IIH and SOL. CONCLUSIONS: This systematic review identified various studies involving OCT to assist diagnosis and management of IH in children with craniosynostosis, IIH, SOL and other pathology, in conjunction with established clinical measures of intracranial pressure. However, no level 1 evidence was identified. Validating prospective studies are, therefore, required to determine optimal OCT parameters in this role and to develop formal clinical guidelines. PROSPERO REGISTRATION NUMBER: CRD42019154254.
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spelling pubmed-83595222021-08-30 Detection of intracranial hypertension in children using optical coherence tomography: a systematic review Rufai, Sohaib R Hisaund, Michael Jeelani, Noor ul Owase McLean, Rebecca J BMJ Open Ophthalmology OBJECTIVES: To evaluate the diagnostic capability of optical coherence tomography (OCT) in children aged under 18 years old with intracranial hypertension (IH). DESIGN: Systematic review. METHODS: We conducted a systematic review using the following platforms to search the keywords ‘optical coherence tomography’ and ‘intracranial hypertension’ from inception to 2 April 2020: Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, PubMed and Web of Science, without language restrictions. Our search returned 2729 records, screened by two independent screeners. Studies were graded according to the Oxford Centre for Evidence-Based Medicine and National Institutes of Health Quality Assessment Tool for observational studies. RESULTS: Twenty-one studies were included. Conditions included craniosynostosis (n=354 patients), idiopathic IH (IIH; n=102), space-occupying lesion (SOL; n=42) and other pathology (n=29). OCT measures included optic nerve parameters, rim parameters (notably retinal nerve fibre layer thickness) and retinal parameters. Levels of evidence included 2b (n=13 studies), 3b (n=4) and 4 (n=4). Quality of 10 studies was fair and 11 poor. There was inconsistency in OCT parameters and reference measures studied, although OCT did demonstrate good diagnostic capability for IH in craniosynostosis, IIH and SOL. CONCLUSIONS: This systematic review identified various studies involving OCT to assist diagnosis and management of IH in children with craniosynostosis, IIH, SOL and other pathology, in conjunction with established clinical measures of intracranial pressure. However, no level 1 evidence was identified. Validating prospective studies are, therefore, required to determine optimal OCT parameters in this role and to develop formal clinical guidelines. PROSPERO REGISTRATION NUMBER: CRD42019154254. BMJ Publishing Group 2021-08-11 /pmc/articles/PMC8359522/ /pubmed/34380720 http://dx.doi.org/10.1136/bmjopen-2020-046935 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Ophthalmology
Rufai, Sohaib R
Hisaund, Michael
Jeelani, Noor ul Owase
McLean, Rebecca J
Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title_full Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title_fullStr Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title_full_unstemmed Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title_short Detection of intracranial hypertension in children using optical coherence tomography: a systematic review
title_sort detection of intracranial hypertension in children using optical coherence tomography: a systematic review
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359522/
https://www.ncbi.nlm.nih.gov/pubmed/34380720
http://dx.doi.org/10.1136/bmjopen-2020-046935
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