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Transition from static culture to stirred tank bioreactor for the allogeneic production of therapeutic discogenic cell spheres

BACKGROUND: Culturing cells as cell spheres results in a tissue-like environment that drives unique cell phenotypes, making it useful for generating cell populations intended for therapeutic use. Unfortunately, common methods that utilize static suspension culture have limited scalability, making co...

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Detalles Bibliográficos
Autores principales:	Rodriguez-Granrose, Daniel, Zurawski, Jeff, Heaton, Will, Tandeski, Terry, Dulatov, Galina, Highsmith, Angelica Adrian, Conen, Mason, Clark, Garrett, Jones, Amanda, Loftus, Hannah, LeBaron, Cameron, Scull, Erin, Farhang, Niloo, Erickson, Isaac, Bingham, Justin, Decaria, Paula, Jones, Nephi, Foley, Kevin T., Silverman, Lara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359559/ https://www.ncbi.nlm.nih.gov/pubmed/34384480 http://dx.doi.org/10.1186/s13287-021-02525-0

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