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Kidney cancer biomarkers and targets for therapeutics: survivin (BIRC5), XIAP, MCL-1, HIF1α, HIF2α, NRF2, MDM2, MDM4, p53, KRAS and AKT in renal cell carcinoma

The incidence of renal cell carcinoma (RCC) is increasing worldwide with an approximate 20% mortality rate. The challenge in RCC is the therapy-resistance. Cancer resistance to treatment employs multiple mechanisms due to cancer heterogeneity with multiple genetic and epigenetic alterations. These c...

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Detalles Bibliográficos
Autores principales:	Li, Fengzhi, Aljahdali, Ieman A. M., Zhang, Renyuan, Nastiuk, Kent L., Krolewski, John J., Ling, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359575/ https://www.ncbi.nlm.nih.gov/pubmed/34384473 http://dx.doi.org/10.1186/s13046-021-02026-1

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