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P2Y2 promotes fibroblasts activation and skeletal muscle fibrosis through AKT, ERK, and PKC

BACKGROUND: Skeletal muscle atrophy and fibrosis are pathological conditions that contribute to morbidity in numerous conditions including aging, cachexia, and denervation. Muscle atrophy is characterized as reduction of muscle fiber size and loss of muscle mass while muscle fibrosis is due to fibro...

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Detalles Bibliográficos
Autores principales: Chen, Mengjie, Chen, Haibing, Gu, Yonggui, Sun, Peng, Sun, Jianxiong, Yu, Haojun, Zheng, Hongliang, Chen, Donghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359595/
https://www.ncbi.nlm.nih.gov/pubmed/34380439
http://dx.doi.org/10.1186/s12891-021-04569-y