TPEN attenuates amyloid-β(25–35)-induced neuronal damage with changes in the electrophysiological properties of voltage-gated sodium and potassium channels

To understand the role of intracellular zinc ion (Zn(2+)) dysregulation in mediating age-related neurodegenerative changes, particularly neurotoxicity resulting from the generation of excessive neurotoxic amyloid-β (Aβ) peptides, this study aimed to investigate whether N, N, N′, N′-tetrakis (2-pyrid...

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Detalles Bibliográficos
Autores principales: Chen, Wen-bo, Wang, Yu-xiang, Wang, Hong-gang, An, Di, Sun, Dan, Li, Pan, Zhang, Tao, Lu, Wan-ge, Liu, Yan-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359616/
https://www.ncbi.nlm.nih.gov/pubmed/34384467
http://dx.doi.org/10.1186/s13041-021-00837-z

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