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Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano

We report a case of a 66-year-old male who presented with a locally advanced primary mucinous adenocarcinoma arising from a fistula-in-ano. The presentation was typical for perianal sepsis and fistula-in-ano with anal pain and chronic discharge. Initial treatments with fistula debridement and seton...

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Autores principales: Au, Jordan, Hulme-Moir, Francis M., Herd, Andrew, Kozman, Mathew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Coloproctology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359692/
https://www.ncbi.nlm.nih.gov/pubmed/32054254
http://dx.doi.org/10.3393/ac.2019.11.19
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author Au, Jordan
Hulme-Moir, Francis M.
Herd, Andrew
Kozman, Mathew A.
author_facet Au, Jordan
Hulme-Moir, Francis M.
Herd, Andrew
Kozman, Mathew A.
author_sort Au, Jordan
collection PubMed
description We report a case of a 66-year-old male who presented with a locally advanced primary mucinous adenocarcinoma arising from a fistula-in-ano. The presentation was typical for perianal sepsis and fistula-in-ano with anal pain and chronic discharge. Initial treatments with fistula debridement and seton were performed. Subsequent review of histology revealed underlying adenocarcinoma, while magnetic resonance imaging (MRI) showed local invasion into the prostate. The patient received neoadjuvant chemoradiotherapy followed by pelvic exenteration to maximize the chance of achieving cure. Features of this case are discussed together with its implications, including treatment guidelines and typical MRI findings.
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spelling pubmed-83596922021-08-16 Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano Au, Jordan Hulme-Moir, Francis M. Herd, Andrew Kozman, Mathew A. Ann Coloproctol Case Report We report a case of a 66-year-old male who presented with a locally advanced primary mucinous adenocarcinoma arising from a fistula-in-ano. The presentation was typical for perianal sepsis and fistula-in-ano with anal pain and chronic discharge. Initial treatments with fistula debridement and seton were performed. Subsequent review of histology revealed underlying adenocarcinoma, while magnetic resonance imaging (MRI) showed local invasion into the prostate. The patient received neoadjuvant chemoradiotherapy followed by pelvic exenteration to maximize the chance of achieving cure. Features of this case are discussed together with its implications, including treatment guidelines and typical MRI findings. Korean Society of Coloproctology 2021-07 2019-11-26 /pmc/articles/PMC8359692/ /pubmed/32054254 http://dx.doi.org/10.3393/ac.2019.11.19 Text en Copyright © 2021 The Korean Society of Coloproctology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Au, Jordan
Hulme-Moir, Francis M.
Herd, Andrew
Kozman, Mathew A.
Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title_full Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title_fullStr Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title_full_unstemmed Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title_short Extensive Resection for Treatment of Locally Advanced Primary Mucinous Adenocarcinoma Arising From Fistula-in-Ano
title_sort extensive resection for treatment of locally advanced primary mucinous adenocarcinoma arising from fistula-in-ano
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359692/
https://www.ncbi.nlm.nih.gov/pubmed/32054254
http://dx.doi.org/10.3393/ac.2019.11.19
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