Modeling Complex Pharmacokinetics of Long‐Acting Injectable Products Using Convolution‐Based Models With Nonparametric Input Functions

The interest in the development and the therapeutic use of long‐acting injectable (LAI) products for chronic or long‐term treatments has grown exponentially. The complexity and the multiphase drug release process represent serious issues for an effective modeling of the PK properties of LAI products...

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Detalles Bibliográficos
Autores principales: Gomeni, Roberto, Bressolle‐Gomeni, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Pharmacokinetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359850/
https://www.ncbi.nlm.nih.gov/pubmed/33606280
http://dx.doi.org/10.1002/jcph.1842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359850/
https://www.ncbi.nlm.nih.gov/pubmed/33606280
http://dx.doi.org/10.1002/jcph.1842

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