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Stereoselective Access to Antimelanoma Agents by Hybridization and Dimerization of Dihydroartemisinin and Artesunic acid
A library of five hybrids and six dimers of dihydroartemisinin and artesunic acid has been synthetized in a stereo‐controlled manner and evaluated for the anticancer activity against metastatic melanoma cell line (RPMI7951). Among novel derivatives, three artesunic acid dimers showed antimelanoma ac...
Autores principales: | Botta, Lorenzo, Cesarini, Silvia, Zippilli, Claudio, Filippi, Silvia, Bizzarri, Bruno Mattia, Baratto, Maria Camilla, Pogni, Rebecca, Saladino, Raffaele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360007/ https://www.ncbi.nlm.nih.gov/pubmed/33792170 http://dx.doi.org/10.1002/cmdc.202100196 |
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