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Discovery of New Carbonyl Reductases Using Functional Metagenomics and Applications in Biocatalysis

Enzyme discovery for use in the manufacture of chemicals, requiring high stereoselectivities, continues to be an important avenue of research. Here, a sequence directed metagenomics approach is described to identify short chain carbonyl reductases. PCR from a metagenomic template generated 37 enzyme...

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Detalles Bibliográficos
Autores principales:	Newgas, Sophie A., Jeffries, Jack W. E., Moody, Thomas S., Ward, John M., Hailes, Helen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360200/ https://www.ncbi.nlm.nih.gov/pubmed/34413714 http://dx.doi.org/10.1002/adsc.202100199

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