2D projection image reconstruction for field free line single-sided magnetic particle imaging scanner: simulation studies

Magnetic Particle Imaging is an imaging modality that exploits the nonlinear response of superparamagnetic iron oxide nanoparticles to a time-varying magnetic field. In the past years, various scanner topologies have been proposed, which includes a single-sided scanner. Such a scanner features all its hardware located on one side, offering accessibility without limitations due to the size of the object of interest. In this paper, we present a proof of concept image reconstruction simulation studies for a single-sided field-free line scanner utilizing non-uniform magnetic fields. Specifically, we implemented a filtered backprojection algorithm allowing a 2D image reconstruction over a field of view of 4 × 4 cm(2) with a spatial resolution of up to 2 mm for noiseless case.