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Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria

OBJECTIVE: To assess the availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria. METHODS: A cross-sectional survey involving 27 private pharmacies, 13 public pharmacies, and 25 private hospital pharmacies in Abuja was conducted using the standardiz...

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Autores principales: Osuafor, Nkeiruka Grace, Ukwe, Chinwe Victoria, Okonta, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360378/
https://www.ncbi.nlm.nih.gov/pubmed/34383799
http://dx.doi.org/10.1371/journal.pone.0255567
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author Osuafor, Nkeiruka Grace
Ukwe, Chinwe Victoria
Okonta, Mathew
author_facet Osuafor, Nkeiruka Grace
Ukwe, Chinwe Victoria
Okonta, Mathew
author_sort Osuafor, Nkeiruka Grace
collection PubMed
description OBJECTIVE: To assess the availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria. METHODS: A cross-sectional survey involving 27 private pharmacies, 13 public pharmacies, and 25 private hospital pharmacies in Abuja was conducted using the standardized World Health Organization/Health Action International methodology. The availability percentage for each pharmacy sector and each medicine was analyzed. The median price ratio (MPR) (ratio of the median price to the international reference prices) of the medicines were evaluated accordingly. Affordability was assessed by calculating the number of days’ wages the lowest-paid unskilled government worker required to purchase a month worth of the standard treatment for a chronic condition. RESULTS: The availability of cardiovascular (CV) medicines ranged from 28.4% (in private hospital pharmacies) to 59.9% (in private pharmacies). There was mixed variability in the mean availability of Originator Brands (OBs) and Lowest Priced Generics (LPGs) anti-diabetic drugs with the highest availability being OBs 36% and LPGs 40.2%, in private pharmacies and public pharmacies, respectively. The availability of global drugs ranged from 49.7% in private hospitals to 68.8% in private pharmacies. Two cardiovascular and four global medicines had greater than 80% availability across the pharmaceutical sectors. The median price ratio for OBs and LPGs was 9.60 and 1.72 for procurement, it was 8.08 and 2.60 in private pharmacies, 13.56 and 2.66 in public hospitals, and 16.38 and 7.89 in private hospitals. The percentage markup on LPG was 49.4% in public hospitals, 51.4% in private pharmacies, and 323% in private hospitals. Only nine medicines in both public hospitals and private pharmacies and two in the private hospital pharmacies required less than the daily wage of the lowest-paid government worker. CONCLUSION: The availability of cardiovascular, diabetes, and global medicines was below 80% across the different pharmaceutical sectors in Abuja and the medicines were unaffordable. Although the prices were generally exorbitant, private pharmacies offered the best options in terms of availability, pricing, and affordability of medicines. Therefore, the results of this study emphasize the pertinence of enforcing policies that facilitate the availability, pricing, and affordability of cardiovascular, diabetes, and global medicines.
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spelling pubmed-83603782021-08-13 Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria Osuafor, Nkeiruka Grace Ukwe, Chinwe Victoria Okonta, Mathew PLoS One Research Article OBJECTIVE: To assess the availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria. METHODS: A cross-sectional survey involving 27 private pharmacies, 13 public pharmacies, and 25 private hospital pharmacies in Abuja was conducted using the standardized World Health Organization/Health Action International methodology. The availability percentage for each pharmacy sector and each medicine was analyzed. The median price ratio (MPR) (ratio of the median price to the international reference prices) of the medicines were evaluated accordingly. Affordability was assessed by calculating the number of days’ wages the lowest-paid unskilled government worker required to purchase a month worth of the standard treatment for a chronic condition. RESULTS: The availability of cardiovascular (CV) medicines ranged from 28.4% (in private hospital pharmacies) to 59.9% (in private pharmacies). There was mixed variability in the mean availability of Originator Brands (OBs) and Lowest Priced Generics (LPGs) anti-diabetic drugs with the highest availability being OBs 36% and LPGs 40.2%, in private pharmacies and public pharmacies, respectively. The availability of global drugs ranged from 49.7% in private hospitals to 68.8% in private pharmacies. Two cardiovascular and four global medicines had greater than 80% availability across the pharmaceutical sectors. The median price ratio for OBs and LPGs was 9.60 and 1.72 for procurement, it was 8.08 and 2.60 in private pharmacies, 13.56 and 2.66 in public hospitals, and 16.38 and 7.89 in private hospitals. The percentage markup on LPG was 49.4% in public hospitals, 51.4% in private pharmacies, and 323% in private hospitals. Only nine medicines in both public hospitals and private pharmacies and two in the private hospital pharmacies required less than the daily wage of the lowest-paid government worker. CONCLUSION: The availability of cardiovascular, diabetes, and global medicines was below 80% across the different pharmaceutical sectors in Abuja and the medicines were unaffordable. Although the prices were generally exorbitant, private pharmacies offered the best options in terms of availability, pricing, and affordability of medicines. Therefore, the results of this study emphasize the pertinence of enforcing policies that facilitate the availability, pricing, and affordability of cardiovascular, diabetes, and global medicines. Public Library of Science 2021-08-12 /pmc/articles/PMC8360378/ /pubmed/34383799 http://dx.doi.org/10.1371/journal.pone.0255567 Text en © 2021 Osuafor et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Osuafor, Nkeiruka Grace
Ukwe, Chinwe Victoria
Okonta, Mathew
Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title_full Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title_fullStr Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title_full_unstemmed Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title_short Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria
title_sort evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in abuja, nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360378/
https://www.ncbi.nlm.nih.gov/pubmed/34383799
http://dx.doi.org/10.1371/journal.pone.0255567
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