Cargando…

Integrated bioinformatics analysis reveals CDK1 and PLK1 as potential therapeutic targets of lung adenocarcinoma

This study is to identify potential biomarkers and therapeutic targets for lung adenocarcinoma (LUAD). GSE6044 and GSE118370 raw data from the Gene Expression Omnibus database were normalized with Robust Multichip Average. After merging these two datasets, the combat function of sva packages was use...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shuzhen, Li, Hua, Cao, Yajie, Geng, Haiying, Ren, Fu, Li, Keyan, Dai, Chunmei, Li, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	5700
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360490/ https://www.ncbi.nlm.nih.gov/pubmed/34397869 http://dx.doi.org/10.1097/MD.0000000000026474

Ejemplares similares

Novel therapeutic compounds for prostate adenocarcinoma treatment: An analysis using bioinformatic approaches and the CMap database
por: Li, Kai, et al.
Publicado: (2020)

Identification of crucial genes associated with lung adenocarcinoma by bioinformatic analysis
por: Dai, Jing-Jing, et al.
Publicado: (2020)

Multiple bioinformatics analysis identifies IGFBP1 as associated with the prognosis of stomach adenocarcinoma
por: Luo, Xiao-Ye, et al.
Publicado: (2023)

ELOVL6 is associated with immunosuppression in lung adenocarcinoma through bioinformatics analysis
por: Chen, Binyu, et al.
Publicado: (2023)

Integrated analysis of ceRNA network in hepatocellular carcinoma using bioinformatics analysis
por: Luo, Yu, et al.
Publicado: (2021)

Identification of LGR4 as a prognostic biomarker in KRAS-mutant lung adenocarcinoma: Evidence from integrated bioinformatics analysis
por: Dodin, Yasmeen
Publicado: (2023)

Association between HMGA1 and immunosuppression in hepatocellular carcinoma: A comprehensive bioinformatics analysis
por: Zhu, Jie, et al.
Publicado: (2023)

Identification of triple gene fusion ALK-LRRN2, LTBP1-ALK, and HIP1-ALK in advanced lung adenocarcinoma and response to alectinib: A case report
por: Ning, Shangkun, et al.
Publicado: (2021)

Identification of key genes in osteosarcoma – before and after CDK7 treatment
por: An, Yang, et al.
Publicado: (2021)

The PITX gene family as potential biomarkers and therapeutic targets in lung adenocarcinoma
por: Zhang, Chunyi, et al.
Publicado: (2021)

LncRNA ALMS1-IT1 is a novel prognostic biomarker and correlated with immune infiltrates in colon adenocarcinoma
por: Lin, Yuning, et al.
Publicado: (2022)

Comprehensive bioinformatics analysis of FXR1 across pan-cancer: Unraveling its diagnostic, prognostic, and immunological significance
por: Xiao, Keyuan, et al.
Publicado: (2023)

Bioinformatics identify the role of chordin-like 1 in thyroid cancer
por: Yu, Jia-Wei, et al.
Publicado: (2023)

A rare double ALK fusion variant EML4-ALK and CDK15-ALK in lung adenocarcinoma and response to crizotinib: A case report
por: Guo, Jun, et al.
Publicado: (2020)

Subcellular localization of β-arrestin1 and its prognostic value in lung adenocarcinoma
por: Li, Xiaowei, et al.
Publicado: (2017)

XXYLT1 methylation contributes to the occurrence of lung adenocarcinoma: Methylation and lung adenocarcinoma
por: Zeng, Hui, et al.
Publicado: (2021)

Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Taxus chinensis against non-small cell lung cancer
por: Zhang, Shujuan, et al.
Publicado: (2023)

GLI1 expression in pancreatic ductal adenocarcinoma correlates the clinical significance and prognosis: A meta-analysis
por: Li, Ruidan, et al.
Publicado: (2020)

Lower expression of LINC00092 in lung adenocarcinoma might mean poorer prognosis: A study based on data mining and bioinformatics
por: Wang, Xin, et al.
Publicado: (2020)

LncRNA DIRC1 is a novel prognostic biomarker and correlated with immune infiltrates in stomach adenocarcinoma
por: Lin, Yuning, et al.
Publicado: (2022)

A web-based nomogram to predict overall survival for postresection leiomyosarcoma patients with lung metastasis
por: Wei, Junqiang, et al.
Publicado: (2023)

A comprehensive bioinformatics analysis of FOXP3 in nonsmall cell lung cancer
por: Zhu, Jianfei, et al.
Publicado: (2022)

Sera total oxidant/antioxidant status in lung cancer patients
por: Xiang, Miao, et al.
Publicado: (2019)

The expression and prognostic significance of Drp1 in lung cancer: A bioinformatics analysis and immunohistochemistry
por: Yu, Lingling, et al.
Publicado: (2019)

Identification of core genes and clinical outcomes in tumors originated from endoderm (gastric cancer and lung carcinoma) via bioinformatics analysis
por: Shi, Yewen, et al.
Publicado: (2021)

Aurora borealis wraps Plk1 and CDK together
por: Mochida, Satoru
Publicado: (2014)

MMP7 as a potential biomarker of colon cancer and its prognostic value by bioinformatics analysis
por: Chen, Li, et al.
Publicado: (2021)

Prognostic significance of volume-based (18)F-FDG PET/CT parameters and correlation with PD-L1 expression in patients with surgically resected lung adenocarcinoma
por: Wang, Dalong, et al.
Publicado: (2021)

Identification of biomarkers of clear cell renal cell carcinoma by bioinformatics analysis
por: Zhang, Ning, et al.
Publicado: (2020)

Bioinformatics identification and validation of aging‑related molecular subtype and prognostic signature in breast cancer
por: Li, Jingtai, et al.
Publicado: (2023)

Prognostic value of aldo-keto reductase family 1 member B10 (AKR1B10) in digestive system cancers: A meta-analysis
por: Liu, Rongqiang, et al.
Publicado: (2021)

Bioinformatics analysis of the key potential ceRNA biomarkers in human thymic epithelial tumors
por: Chen, Kegong, et al.
Publicado: (2021)

The specific phagocytosis regulators could predict recurrence and therapeutic effect in thyroid cancer: A study based on bioinformatics analysis
por: Hou, Changran, et al.
Publicado: (2023)

Metastasis to the appendix from adenocarcinoma of the ascending colon: A case report
por: Li, Yingjie, et al.
Publicado: (2017)

Determining the mechanism of action of the Qishan formula against lung adenocarcinoma by integration of network pharmacology, molecular docking, and proteomics
por: Geng, Xue, et al.
Publicado: (2023)

Identification of pyroptosis-related gene signature for predicting prognosis of patients with pancreatic cancer using bioinformatics
por: Xu, Zhongbo, et al.
Publicado: (2022)

Clinicopathological, radiographic, and oncogenic features of primary pulmonary enteric adenocarcinoma in comparison with invasive adenocarcinoma in resection specimens
por: Zhao, Long, et al.
Publicado: (2017)

NDUFA4L2 is a novel biomarker for colorectal cancer through bioinformatics analysis
por: Lin, Yuning, et al.
Publicado: (2023)

Screening and identification of key genes between liver hepatocellular carcinoma (LIHC) and cholangiocarcinoma (CHOL) by bioinformatic analysis
por: Kang, Xindan, et al.
Publicado: (2020)

Identification of potential biomarkers and candidate therapeutic drugs for clear cell renal cell carcinoma by bioinformatic analysis and reverse network pharmacology
por: Meng, Zhuo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qd54ucq7sh6575k526vdoe31p7