Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs

We investigated a hereditary cerebellar ataxia in Belgian Shepherd dogs. Affected dogs developed uncoordinated movements and intention tremor at two weeks of age. The severity of clinical signs was highly variable. Histopathology demonstrated atrophy of the CNS, particularly in the cerebellum. Combi...

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Detalles Bibliográficos
Autores principales: Christen, Matthias, Högler, Sandra, Kleiter, Miriam, Leschnik, Michael, Weber, Corinna, Thaller, Denise, Jagannathan, Vidhya, Leeb, Tosso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360551/
https://www.ncbi.nlm.nih.gov/pubmed/34339417
http://dx.doi.org/10.1371/journal.pgen.1009716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360551/
https://www.ncbi.nlm.nih.gov/pubmed/34339417
http://dx.doi.org/10.1371/journal.pgen.1009716

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