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Deletion of the SELENOP gene leads to CNS atrophy with cerebellar ataxia in dogs
We investigated a hereditary cerebellar ataxia in Belgian Shepherd dogs. Affected dogs developed uncoordinated movements and intention tremor at two weeks of age. The severity of clinical signs was highly variable. Histopathology demonstrated atrophy of the CNS, particularly in the cerebellum. Combi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360551/ https://www.ncbi.nlm.nih.gov/pubmed/34339417 http://dx.doi.org/10.1371/journal.pgen.1009716 |