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A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes
Mutations are known to cause perturbations in essential functional features of integral membrane proteins, including ion channels. Even restricted or point mutations can result in substantially changed properties of ion currents. The additive effect of these alterations for a specific ion channel ca...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360568/ https://www.ncbi.nlm.nih.gov/pubmed/34383746 http://dx.doi.org/10.1371/journal.pcbi.1009233 |