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Model checking via testing for direct effects in Mendelian Randomization and transcriptome-wide association studies

It is of great interest and potential to discover causal relationships between pairs of exposures and outcomes using genetic variants as instrumental variables (IVs) to deal with hidden confounding in observational studies. Two most popular approaches are Mendelian randomization (MR), which usually...

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Detalles Bibliográficos
Autores principales:	Deng, Yangqing, Pan, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360571/ https://www.ncbi.nlm.nih.gov/pubmed/34339418 http://dx.doi.org/10.1371/journal.pcbi.1009266

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