Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting

RATIONALE: Murine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the safety and feasibility of this approach in a relev...

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Detalles Bibliográficos
Autores principales: Magee, Kara, Marsh, Ian R., Turek, Michelle M., Grudzinski, Joseph, Aluicio-Sarduy, Eduardo, Engle, Jonathan W., Kurzman, Ilene D., Zuleger, Cindy L., Oseid, Elizabeth A., Jaskowiak, Christine, Albertini, Mark R., Esbona, Karla, Bednarz, Bryan, Sondel, Paul M., Weichert, Jamey P., Morris, Zachary S., Hernandez, Reinier, Vail, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360580/
https://www.ncbi.nlm.nih.gov/pubmed/34383787
http://dx.doi.org/10.1371/journal.pone.0255798

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