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Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells

The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral infection contribute to the development of EBV-associated tumors. Here we show that the Hippo signaling effectors, YAP and TAZ, promote lytic EBV re...

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Detalles Bibliográficos
Autores principales:	Van Sciver, Nicholas, Ohashi, Makoto, Pauly, Nicholas P., Bristol, Jillian A., Nelson, Scott E., Johannsen, Eric C., Kenney, Shannon C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360610/ https://www.ncbi.nlm.nih.gov/pubmed/34339458 http://dx.doi.org/10.1371/journal.ppat.1009783

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