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Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy
Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network extending from the nucleus to the cell periphery, which provides resistance to mechanical stresses. Mutations in keratin genes are related t...
Autores principales: | Weber, Miriam S, Eibauer, Matthias, Sivagurunathan, Suganya, Magin, Thomas M, Goldman, Robert D, Medalia, Ohad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360650/ https://www.ncbi.nlm.nih.gov/pubmed/34323216 http://dx.doi.org/10.7554/eLife.70307 |
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