Cargando…
A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease
BACKGROUND: The multifactorial nature of non-alcoholic fatty liver disease cannot be explained solely by genetic factors. Recent evidence revealed that DNA methylation changes take place at proximal promoters within susceptibility genes. This emphasizes the need for integrating multiple data types t...
Autores principales: | Diels, Sara, Cuypers, Bart, Tvarijonaviciute, Asta, Derudas, Bruno, Van Dijck, Evelien, Verrijken, An, Van Gaal, Luc F., Laukens, Kris, Lefebvre, Philippe, Ceron, Jose J., Francque, Sven, Vanden Berghe, Wim, Van Hul, Wim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360816/ https://www.ncbi.nlm.nih.gov/pubmed/34389043 http://dx.doi.org/10.1186/s13148-021-01142-1 |
Ejemplares similares
-
Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review
por: Van Dijck, Evelien, et al.
Publicado: (2022) -
Copy number variant analysis and expression profiling of the olfactory receptor-rich 11q11 region in obesity predisposition
por: Diels, Sara, et al.
Publicado: (2020) -
Serum paraoxonase 1 (PON1) measurement: an update
por: Ceron, Jose J, et al.
Publicado: (2014) -
Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence
por: Logie, Emilie, et al.
Publicado: (2021) -
Mining the human proteome for conserved mechanisms
por: Naulaerts, Stefan, et al.
Publicado: (2015)