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PD-L1 amplification is associated with an immune cell rich phenotype in squamous cell cancer of the lung

Gene amplification is considered to be one responsible cause for upregulation of Programmed Death Ligand-1 (PD-L1) in non-small cell lung cancer (NSCLC) and to represent a specific molecular subgroup possibly associated with immunotherapy response. Our aim was to analyze the frequency of PD-L1 ampli...

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Detalles Bibliográficos
Autores principales: Goldmann, Torsten, Marwitz, Sebastian, Nitschkowski, Dörte, Krupar, Rosemarie, Backman, Max, Elfving, Hedvig, Thurfjell, Viktoria, Lindberg, Amanda, Brunnström, Hans, La Fleur, Linnea, Mezheyeuski, Artur, Mattsson, Johanna Sofia Margareta, Botling, Johan, Micke, Patrick, Strell, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360842/
https://www.ncbi.nlm.nih.gov/pubmed/33576873
http://dx.doi.org/10.1007/s00262-020-02825-z