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Interplay of stromal tumor-infiltrating lymphocytes, normal colonic mucosa, cancer-associated fibroblasts, clinicopathological data and the immunoregulatory molecules of patients diagnosed with colorectal cancer

A total of 94 patients with colorectal cancer (CRC) were included in this study. Lymphocytic infiltration of CD45(+) cells in the normal colon was more pronounced than that in the paired tumor stroma (p = 0.0008). The mean immunoscore of CD45(+)TILs was decreased in CRC compared with the controls (p...

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Detalles Bibliográficos
Autores principales: Zadka, Łukasz, Chabowski, Mariusz, Grybowski, Damian, Piotrowska, Aleksandra, Dzięgiel, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360892/
https://www.ncbi.nlm.nih.gov/pubmed/33625532
http://dx.doi.org/10.1007/s00262-021-02863-1